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We're back in business here at the Science Museum (although the building is still closed to the public until next Friday), just in time to report some good news.

Ouch: Taking one for the team?
Ouch: Taking one for the team?
Courtesy Spamily

The CDC reported yesterday that 77.4% of US children between the ages of 19 months and three years received all their recommended vaccinations in 2007. That's a slight improvement over the 2006 statistic. There are big regional variations in coverage, and children living below the poverty line are slightly less likely to be fully vaccinated, but overall less than 1% of US kids received no immunizations at all.

What are the recommended shots?

  • Four or more doses of diphtheria, tetanus toxoid, and any acellular pertussis vaccine, or DTaP
  • Three or more doses of polio vaccine
  • At least one dose of measles, mumps, and rubella (MMR) vaccine
  • At least three doses of Haemophilus influenzae type b vaccine
  • At least three doses of hepatitis B vaccine
  • At least one dose of varicella vaccine

Some folks don't vaccinate their kids--particularly against measles, mumps, and rubella (MMR)--because they worry that the vaccine is linked to autism. That theory has been debunked many times, in many countries, but it persists. On Wednesday, researchers from Columbia University and the CDC offered up another study showing zero causal relationship between the MMR vaccine and autism (or gastrointestinal problems.) So kids, roll up your sleeves at those back-to-school physicals and get your shots. It sucks, but it beats getting measles.

On the other hand, evidence is mounting to show that flu shots don't work well to protect people over 70. Older people have a lesser immune response to the vaccine and don't develop as much immunity. But the very old and the very young also account for the highest number of flu deaths. So what to do? According to the NT Times article:

"Dr. Simonsen, the epidemiologist at George Washington, said the new research made common-sense infection-control measures — like avoiding other sick people and frequent hand washing — more important than ever. Still, she added, “The vaccine is still important. Thirty percent protection is better than zero percent.”

Another way to protect the elderly is to vaccinate preschoolers. Not only are they likely to pick up the flu before other members of the family, but there's some evidence that preschoolers are actually the drivers of annual influenza outbreaks. Stop the flu in young kids, and you might just stop it for everyone else, too.


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Do as we say, or we'll kill your family: Some animal activists are attacking researchers' homes.
Do as we say, or we'll kill your family: Some animal activists are attacking researchers' homes.
Courtesy charmingly_busy

(With the Republican National Convention literally across the street, the Science Museum of Minnesota will be closed starting Friday, August 29. But Science Buzz marches on! To honor our convention guests, I’ll be posting entries focusing on issues where science and politics overlap. Hopefully this will spur some discussion. Or at least tick some people off. Previous entries here, here and here.)

5:30 Saturday morning. The pre-dawn quiet is shattered by firebombs exploding almost simultaneously in different parts of the town. One is set under a car in a driveway, apparently trying to ignite the fuel tank. The others ignite on the porch of a family home, setting it on fire, forcing a husband, wife and their two children to climb out of a second-floor window to escape. All this follows a pattern of death threats, break-ins, harassment and intimidation.

A movie, perhaps? A war-torn foreign country beset by extremists?

Nope. Santa Cruz, California. The target: scientists.

Some groups of activist have long protested the use of animals in experiments. Most of these protests have been peaceful social and political action, and they’ve had results—the care of lab animals has improved, and many cosmetic companies no longer test their products on animals.

But some activists crossed the line into crime and violence, breaking into labs and destroying equipment. And now they have escalated to attacking researchers and their families in their homes. In one instance, masked intruders broke into a professor’s home and disrupted his daughter’s birthday party. Classy.

The scientists being targeted are biomedical researchers, trying to find cures for diseases like cancer and AIDS. If they are successful in shutting down medical research, then as a result millions upon millions of people will die slow, painful, and preventable deaths, thanks to their efforts.

(And it’s not just medical research—in one instance, activists wanted to stop a university from testing the safety of…pet food. That’s right—these lunatics who claim to be advocating on behalf of animals, want to make it harder for companies to ensure the safety of pet food. Brilliant.)

While some groups focus their activity on labs that conduct tests on happy little monkeys or cute fluffy bunnies, others draw no such distinctions. Some have targeted researchers using fruit flies.

Worried that this terrorism might persuade researchers to leave the field, or dissuade young scientists from entering it, the US Congress in 2006 passed the Animal Enterprise Terrorism Act to protect researchers. However, there have not yet been any prosecutions under this legislation.

(Meanwhile, in response to the recent attacks, the California state legislature is pushing through its own ordinance. UCLA has gone on the offensive and is suing people involved in intimidating researchers,)

This is not how we do things in this country. If you think an activity should be limited or outlawed, speak up. Petition the government. Elect officials who agree with you. But do not take the law into your own hands, resort to terrorism, or try to blow up little children.

When I was a kid, I used to do stupid kid things. And my saintly Mother in frustration would cry out, “What’s the matter with you? Do you sit on your brains?” I would ask the same question of these losers—except that would imply they had brains to begin with. And that would seem to give them entirely too much credit.


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Women in science: Should government-funded labs make a point of hiring an equal number of men and women?
Women in science: Should government-funded labs make a point of hiring an equal number of men and women?
Courtesy NIOSH—Nat’l Inst. For Occupational Safety & Health

(With the Republican National Convention literally across the street, the Science Museum of Minnesota will be closed starting Friday, August 29. But Science Buzz marches on! To honor our convention guests, I’ll be posting entries focusing on issues where science and politics overlap. Hopefully this will spur some discussion. Or at least tick some people off. Previous entry here.)

Affirmative action. Another nice, safe topic that we have talked about before, though in a different context.

In 1972, Congress passed an education bill which included, among its amendments, the following language:

"No person in the United States shall, on the basis of sex, be excluded from participation in, be denied the benefits of, or be subjected to discrimination under any education program or activity receiving Federal financial assistance."

Certainly sounds fair. But this amendment, known as “Title IX,” has caused its share of headaches. The law states that men and women should have equal opportunity in educational activities. But “opportunity” is often hard to measure. If few women partake in a given activity, is it because of discrimination? Because of lack of interest? Or, in the case of athletics, because of physical limitations?

Hard to say sometimes. So instead, the courts look at outcomes. If significantly more men than women are participating in a activity, the courts tell the schools they need to get the numbers in line. Usually this means trying to increase women’s participation. Too often, however, it has meant cutting support for men – a surreal Harrison Bergeron result if ever there was one.

This same “logic” is now to be applied to academic science departments. Under pressure from Congress, several federal science agencies are now looking for discrimination in college science departments. And, since motive is hard to prove, there are fears that courts will again fall back to looking solely at results, and force schools to hire equal numbers of male and female scientists, regardless of their qualifications. Which is fairly antithetical to the pure meritocracy science is supposed to be.

No one wants discrimination. But it would be a national tragedy if the pursuit of political correctness ended up hindering American science, just as science has become more important than at any moment in human history.

New York Times reporter John Tierney has reviewed the National Academy of Science’s report on discrimination, and has found very little evidence of bias. And, as we discussed earlier, many women do not pursue math careers, not because of discrimination, but simply because of individual choice.

This appears to be a solution in search of a problem.


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Like this: But way better. And stuff.
Like this: But way better. And stuff.
Courtesy Library of Congress
Protect your grills, everybody, because the future is looking to get all up in them again!

Over the next two years, the oldest known copies of biblical documents, the Dead Sea Scrolls, will be digitally scanned and placed online for all the world to examine at their leisure.

Well, not all the world. Just the parts with computers and access to the Internet, and just those people who know and care that the Dead Sea Scrolls are available for public study. So not all the world at all.

The first of the scrolls were discovered accidentally in a cave in the West Bank by a goatherd in 1947. Over the next thirty years, more scrolls—about 1000 documents in total—were found in 11 caves in the area. The documents include texts from the Hebrew Bible, dating to before 100 AD. The scrolls are also reported to contain an astonishing number of recipes and very dirty jokes.

The thousands of fragments of the scrolls were photographed in their entirety (up to that point) only once, in the 1950s. Many of those photographs are now crumbling, and so, despite the arguments of some Luddites who are no doubt on the way out themselves, scholars are taking advantage of this amazing time we live in (the future), and are subjecting the whole of the scroll collection to some fancy pants scanning.

The images of the texts will be taken in very high resolution and with varying wavelengths of light, highlighting details not readily visible to the naked eye.

The physical scrolls will be beginning a tour of the United States next month at the Jewish Museum of New York.


The original Minifig: mocked horribly by later generations of minifigures, but, fortunately, incapable of feeling emotion of any kind.
The original Minifig: mocked horribly by later generations of minifigures, but, fortunately, incapable of feeling emotion of any kind.
Courtesy Wakuran
I'm a couple days late here, but it's time we recognized the Lego minifigure's 30th birthday.

That's right—on August 25th, 1978, Lego introduced the little yellow Lego guy. Lego had been manufacturing plastic interlocking bricks since 1949, allowing children across the world to practice engineering without realizing that they shouldn't be having fun, but it wasn't until 78 that they sold a little human like thing to enjoy our Lego creations.

Technically there were minifigures available in 1974, but the were faceless, armless pylon-men, and they couldn't enjoy anything. 1978 brought the lovable little man we know today.

Wired's piece on the birthday features this epic video embed:


And, yes, that does make me want to buy a bunch of Lego friends, and have a party for the 20th century, but I thought I'd leave you with a different, though no less triumphant, Lego celebration. Enjoy.



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If you were a scientist, which scientist would you rather be?

The guy who invents and tests new high-powered water guns?

or

The guy who invented the synthesizer guitar?

It’s a really tough call...


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A motorcycle race...: In the future!
A motorcycle race...: In the future!
Courtesy Private Custard
A student in the transportation program of the < a href=http://www.artcenter.edu/>Art Center College of Design has invented a brand new paradox: a concept-motorcycle that is somehow simultaneously totally awesome and utterly, hopelessly dorky.

It’s a mega future tri-moto electro cyber transporto THX laser blade runner terminatrix rideable machine.

I guess they call it the conceptual exoskeleton motorcycle, Deus Ex Machina. But I think my name for it is still less dorky.

What? You want an actual description of the vehicle? Well, you could just click on the long link above, and leave Science Buzz forever, but we like you here. So at least read the rest of the post before you go.

The Deus Ex Machina is sort of a wheeled tripod, with straps and an integrated helmet to secure the rider. It parks in an upright position, but once it starts moving, the “arms” of the tripod extend forward, so the rider is in a sort of superman position. The motorcycle steers according to the rider’s body position, translating movement to 36 pneumatic muscles. Like, um, Robocop, I think.

The whole vehicle is powered with electricity, using fancy lithium ion batteries and ultracapacitors (check out ARTiFactor’s post for more on ultracapacitors), and is capable of reaching speeds of around 75 mph.

The Ultra Deus Mega Electromachina motorcycle is still very much conceptual, however. That is to say, while all the technological components exist (in some form) the vehicle itself only exists as a computer rendering at the moment. So it’s probably not very fun to ride. The designer maintains that it’s not a fantasy: “It’s a green vehicle,” he says, “and all of the numbers are based in the real world.”

The design itself seems more based in the Minority Report world, but whatev.

There’s a video here, too.


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Bakers Yeast: Saccharomyces cerevisiae
Bakers Yeast: Saccharomyces cerevisiae
Courtesy Hellahulla

To easily manufacture drugs

Researchers at the California Institute of Technology have developed a novel way to churn out large quantities of drugs, including antiplaque toothpaste additives, antibiotics, nicotine, and even morphine, using mini biofactories--in yeast.

Take one part baker's yeast

Christina D. Smolke, an assistant professor of chemical engineering at Caltech, along with graduate student Kristy Hawkins, genetically modified common baker's yeast (Saccharomyces cerevisiae) so that it contained the genes for several plant enzymes.

Add some plant genetics

The enzymes allow the yeast to produce a chemical called reticuline, which is a precursor for many different classes of benzylisoquinoline alkaloid (BIA) molecules.

One step away from pharmacologically useful molecules

BIA molecules exhibit a wide variety of pharmacological activities, including antispasmodic effects, pain relief, and hair growth acceleration. Other BIAs have shown anticancer, antioxidant, antimalarial, and anti-HIV potential.

Learn more

A paper describing the research, now available online, will be featured as the cover article of the September issue of Nature Chemical Biology: Production of benzylisoquinoline alkaloids in Saccharomyces cerevisiae.
Source: e! Science News


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Ask not...: It tolls for thee, bro, it tolls for thee.
Ask not...: It tolls for thee, bro, it tolls for thee.
Courtesy carl.jones
Just messin’, y’all!

Only some of us will die on September 10th! And that’s only because we were going to die anyway. There will be sudden heart attacks, tragic car accidents, hilarious full-body prolapses, and possibly some mysterious cases of spontaneous combustion, and none of that will have anything to do with the Large Hadron Collider turning on on the tenth of September.

That’s right, everyone, you can stop holding your breath, and start crossing your fingers, because the LHC now has a date for its first proton collision.

Some people have raised concerns that turning on the LHC could lead to the destruction of the earth in one of several very sciencey ways. Other people have shouted down these jokers, however, because they are very, very, very probably wrong.

And if the world doesn’t end, well, we’ll probably learn all sorts of rad things about the nature of the universe. We might even get some visitors from the future. But I might put a larger bet on the destruction of the solar system (but, you know, fingers crossed).

So, Buzzketeers, on September 10, do your best to protect yourself from the everyday dangers of existence. Wrap your head in packing foam, fill your tummy with starch-based peanuts, and keep yourself wet and/or naked to prevent sparks catching in your clothing and hair, because you probably won’t want to miss what’s coming out of the LHC.


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Researchers at Swansea University, in the UK, are developing an antibiotic that can fight the MRSA superbug. And they're using superbugs to do it. OK, not superbugs. They're using the secretions from the maggots of the common green bottle fly.

A cage match I'm not sure I want to see: Maggots secrete a compound that can fight superbugs, including 12 strains of MRSA, E. coli, and C. difficile.
A cage match I'm not sure I want to see: Maggots secrete a compound that can fight superbugs, including 12 strains of MRSA, E. coli, and C. difficile.
Courtesy National Institutes of Health

Super gross? Sure. And you won't see an ad for this antibiotic (Seraticin) on TV anytime soon. It takes some 20 maggots to make a single drop of the drug. So scientists have to fully identify it, figure out a way to synthesize it in the lab, test it on human cells, and put it through a clinical trial.

In the meantime, using live maggots on infected wounds is a time-tested way of beating infections. Dr. Alun Morgan, of ZooBiotic Ltd, told the BBC,

"Maggots are great little multitaskers. They produce enzymes that clean wounds, they make a wound more alkaline which may slow bacterial growth and finally they produce a range of antibacterial chemicals that stop the bacteria growing."

How effective are maggots? The University of Manchester has been doing research on diabetic patients with MRSA-contaminated foot ulcers. The patients treated with maggots were mostly cured within three weeks. Patients who got more conventional treatment needed 28 weeks.

So give maggots a big shout out. And then check these other stories:
"NHS 'needs to use more maggots'"
Prescription insects
Fun with beetles