Stories tagged vaccination

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Take your time and think it through, guy: But don't worry about the MMR vaccine.
Take your time and think it through, guy: But don't worry about the MMR vaccine.
Courtesy paul+photos=moody
Let’s be careful how we put our words together, everybody.

I mean, when I get dressed in the morning, I know that I want to get underwear, socks, pants, and at least one shirt onto my body. However, if I were to forgo all rules of dressing order and arrangement, I might give off the wrong message: i.e., I’m crazy, and possibly dangerous to be around.

Why would I take any less care with my precious, precious words?

Because I’m pretty lazy, I don’t generally read most (any) of the articles on science that I come across every day. Instead, I read only the headlines. Or, better yet, I have them read to me—that way I can rest my head on my desk while I’m taking in the news. It’s very important, then, that all headlines are clearly worded. Otherwise I could dictate a Science Buzz post that is even more factually inaccurate than my posts normally are. That’s dangerous territory.

Survey confirms parents’ fears, confusion over autism.”

I looked at that headline, saw the word “vaccine” in the body, and thought, “Oh, snap! Vaccines do cause autism?” Because, that’s what parents’ are afraid of, after all.

Nope. The existence of parents’ fear and confusion over autism is what has been confirmed here. The actual connection between vaccinations and autism remains non-existent.

A recent study found that a significant percentage of parents still believe that the measles, mumps and rubella vaccine can cause autism, or are at least uncertain and fearful that such a connection does exist. This is despite the fact that scientists can establish no connection between early childhood vaccines and the development of autism.

The fear that early childhood vaccinations lead to an increased risk for autism originated from a 1998 study that linked autism to a particular mercury-based preservative in the MMR vaccine. It was later revealed that the study was based on bad research, and it was retracted by most of its authors and disowned by its publisher. In 2001, manufacturers of the MMR vaccine began removing the preservative from their vaccines anyway—and that’s probably not a bad thing, but it hasn’t lead to any decrease in the occurrence of autism. And people are still worried about the vaccine anyway.

This confusion wouldn’t be such a big deal, except that the better-safe-than-sorry attitude towards not having children vaccinated has lead to a resurgence in diseases that had essentially been eradicated in areas where the vaccine is available.

Science Buzz has had a lot of conversation on this subject already, and, if you’re interested, I’d recommend you check out some of the other posts on autism and vaccinations.

It probably won't be ready for the winter flu shot season, but researchers in Japan are developing a new syringe that works without a needle. Here's a link to video about this new concept. I know, it takes all the thrills and danger out of visiting the clinic, but think of all the tears that will be saved by five-year-olds getting their pre-kindergarten vaccinations!

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We're back in business here at the Science Museum (although the building is still closed to the public until next Friday), just in time to report some good news.

Ouch: Taking one for the team?
Ouch: Taking one for the team?
Courtesy Spamily

The CDC reported yesterday that 77.4% of US children between the ages of 19 months and three years received all their recommended vaccinations in 2007. That's a slight improvement over the 2006 statistic. There are big regional variations in coverage, and children living below the poverty line are slightly less likely to be fully vaccinated, but overall less than 1% of US kids received no immunizations at all.

What are the recommended shots?

  • Four or more doses of diphtheria, tetanus toxoid, and any acellular pertussis vaccine, or DTaP
  • Three or more doses of polio vaccine
  • At least one dose of measles, mumps, and rubella (MMR) vaccine
  • At least three doses of Haemophilus influenzae type b vaccine
  • At least three doses of hepatitis B vaccine
  • At least one dose of varicella vaccine

Some folks don't vaccinate their kids--particularly against measles, mumps, and rubella (MMR)--because they worry that the vaccine is linked to autism. That theory has been debunked many times, in many countries, but it persists. On Wednesday, researchers from Columbia University and the CDC offered up another study showing zero causal relationship between the MMR vaccine and autism (or gastrointestinal problems.) So kids, roll up your sleeves at those back-to-school physicals and get your shots. It sucks, but it beats getting measles.

On the other hand, evidence is mounting to show that flu shots don't work well to protect people over 70. Older people have a lesser immune response to the vaccine and don't develop as much immunity. But the very old and the very young also account for the highest number of flu deaths. So what to do? According to the NT Times article:

"Dr. Simonsen, the epidemiologist at George Washington, said the new research made common-sense infection-control measures — like avoiding other sick people and frequent hand washing — more important than ever. Still, she added, “The vaccine is still important. Thirty percent protection is better than zero percent.”

Another way to protect the elderly is to vaccinate preschoolers. Not only are they likely to pick up the flu before other members of the family, but there's some evidence that preschoolers are actually the drivers of annual influenza outbreaks. Stop the flu in young kids, and you might just stop it for everyone else, too.

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The face of the enemy: Know it well.  They wait, biding their time, building up the strength of their numbers, and of their horrible, secret weapon of doom!
The face of the enemy: Know it well. They wait, biding their time, building up the strength of their numbers, and of their horrible, secret weapon of doom!
Courtesy foxypar4

That’s sheep farts to you and me, and apparently it’s a major problem. There are over one billion sheep in the world. They spend their day, standing in the meadow, gamboling playfully, watching Sam, the big shaggy cartoon sheep dog, foil the ingenious but inevitably futile efforts of Ralph, the wolf who looks suspiciously like a coyote.

And eating. Grass is what sheep eat. Unfortunately, they can’t digest it. Instead, they have little tiny microbes in their stomachs (four stomachs per sheep) that break down the plant fiber for them.

Unfortunately, microbes are rude little creatures, emitting methane gas with every mouthful and nary an “excuse me” to be heard. The methane builds up inside the ovine until it escapes in the form of sheep farts. (And, seriously, if you ever have a chance to write an essay that can justifiably include the phrase “sheep farts,” then you should seize the opportunity and use the term just as often as you possibly can.)

Anyway, the methane (a.k.a. sheep farts) gets into the atmosphere where, some would have it, it will trap heat and warm the globe and eventually destroy civilization as we know it. This may or may not be a bad thing, but I personally would hate to see my home destroyed just because of sheep farts.

Fortunately some researchers in New Zealand have come to our rescue. These plucky kiwis are tackling the sheep fart menace head-on, trying to develop a vaccination that will improve the microbes’ table manners. An anxious world holds its breath – partly in anticipation of the coming breakthrough in sheep fart technology, but mostly in response to the sheep farts themselves.

The government began an unprecedented effort Friday to give vaccine critics a say in shaping how the nation researches safety questions surrounding immunizations.

A government-appointed working group is charged with picking the most important safety questions for the Centers for Disease Control and Prevention to research over the next five years. (Wired News)

Measles Outbreaks

by Laurie on Apr. 07th, 2008
in
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Measles rash: This young boy has a 3 day old rash caused by the measles virus.
Measles rash: This young boy has a 3 day old rash caused by the measles virus.
Courtesy CDC PHIL #1152

Recently, twelve people were diagnosed with measles in San Diego, another nine in Pima County Arizona. In Salzburg, Austria 180 people have been infected during a recent outbreak. Thankfully there haven’t been any deaths from these latest outbreaks.

People in Nigeria’s northern Katsina state have not been as lucky. At the moment they are facing a measles epidemic which has killed nearly two hundred children in the past three months, and infected thousands.

What’s going on?
It seams that parents, for a variety of reasons, are fearful of giving their children vaccinations. For nearly everyone, the measles vaccination is safe and effective and if you want more information about the vaccine click here. Measles outbreaks aren’t very common in the U.S., fewer than 100 per year. But in the pre-vaccine era, 3-4 million measles cases occurred every year in the US. This resulted in approximately 450 deaths, 28,000 hospitalizations and 1,000 children with chronic disabilities from measles encephalitis each year. These two outbreaks in the US serve as a reminder that unvaccinated people remain at risk for measles and that measles spreads rapidly without proper controls.

According to the WHO, around the world measles still kills 250,000 people each year. Most of these deaths occur in undeveloped nations where people don’t have access to vaccinations and healthcare. But it appears the problem in both Austria and Nigeria are unvaccinated children. In Nigeria many parents are afraid to vaccinate as reported in the VOA:

Katsina state's director of disease control, Halliru Idris, tells VOA that the outbreak is mostly affecting young people who have not been immunized. "I can tell you that over 95 percent of all the children that have measles are those whose parents have not allowed them to receive immunization," he said.
A handful of radical Islamic clerics instigated a boycott of infant vaccinations in northern Nigeria in 2003 and 2004, alleging that immunization was a western ploy to render Muslim girls infertile. Though the dispute has been resolved, parents still tend to avoid immunization.

In Austria officials fear that school administrators at the private school where the outbreak began advised parents against vaccinating their students. An investigation is ongoing.

So what should we do?
In Iowa the public health response to one imported measles case cost approximately $150,000. Should parents who choose not to vaccinate their children be responsible for these expenses? How do we balance personal choice and the good of the community?

Some microbes are resistant to antibiotics. Researchers in England have developed a way to change the molecular structure of antibiotics to make them more effective against these “superbugs.”

Over 90 per cent of the subjects in the phase 1 trials developed an immune response to HIV. The study was conducted by researchers at Karolinska Institutet (KI), Karolinska University Hospital and the Swedish Institute for Infectious Disease Control (SMI).
Read more about the results from Swedish study of HIV vaccine at the Karolinska Institutet web site.

A study published in the most recent issue of Pediatrics shows that the rate of autism and related disorders increased even as thimerosal (a mercury preservative) was eliminated from vaccines and fewer children received the MMR vaccine. The study looked at 28,000 children over 11 years. This and other studies confirm that there is no evidence to suggest that the MMR vaccine increases the risk of autism.

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HVP Vaccine: Vaccine approved to protect against cervical cancer
HVP Vaccine: Vaccine approved to protect against cervical cancer
Courtesy Centers for Disease Control and Prevention

Should pre-teen girls be vaccinated against cervical cancer?

This is what a US federal medical panel recommended. The decision comes on the heels of US government approval earlier in June of the vaccine, Gardasil.

The Advisory Committee on Immunization Practices (ACIP) recommended the first vaccine developed to prevent cervical cancer and other diseases in females caused by certain types of genital human papillomavirus (HPV). The vaccine, Gardasil®, protects against four HPV types, which are responsible for 70% of cervical cancers and 90% of genital warts. This HPV vaccine was recently licensed by the Food and Drug Administration (FDA) for use in girls/women, ages 9-26 years.

Some FAQ from the Centers for Disease Control and Prevention.

How common is cervical cancer in the United States (U.S.)? How many women die from it?
The American Cancer Society estimates that in 2006, over 9,700 women will be diagnosed with cervical cancer and 3,700 women will die from this cancer in the U.S.

What HPV types does the vaccine protect against?
The new HPV vaccine protects against the two HPV types that cause most (70%) cervical cancers (types 16 and 18), and the two HPV types that cause most (90%) genital warts (types 6 and 11).
About 30% of cervical cancers will not be prevented by the vaccine. Also, the vaccine does not prevent about 10% of genital warts

Why is HPV vaccine recommended for such young girls?
Ideally, females should get the vaccine before they are sexually active—since this vaccine is most effective in girls/women who have not yet acquired any of the HPV vaccine types. Girls/women who have not been infected with any vaccine HPV type will get the full benefits of the vaccin

Is the HPV vaccine safe?
The FDA has approved the HPV vaccine as safe and effective. This vaccine has been tested in over 11,000 females (ages 9-26 years) in many countries around the world. These studies have shown no serious side effects. The most common side effect is soreness at the injection site

How effective is this vaccine?
The vaccine has mainly been studied in young women who had not been exposed to any of the four vaccine HPV types. These studies found the vaccine to be 100% effective in preventing cervical precancers caused by the vaccine HPV types. These studies also found it to be almost 100% effective in preventing precancers of the vulva and vagina, and genital warts that are caused by the vaccine HPV types. The vaccine was less effective in young women who had already been exposed to a vaccine HPV type. This vaccine does not treat existing HPV, genital warts, precancers or cancers. Centers for Disease Control and Prevention

Bill Gates

According to The National Cervical Cancer Coalition women in developing countries account for about 85 percent of both the yearly cases of cervical cancer (estimated at 493,000 cases worldwide) and the yearly deaths from cervical cancer (estimated at 273,500 deaths worldwide).
In the majority of developing countries, cervical cancer remains the number-one cause of cancer-related deaths among women.
Backed by a $27.8 million grant from the Bill and Melinda Gates Foundation, the non-profit international health group, PATH, will launch a five-year effort to distributing Gardasil to women starting in India, Uganda, Peru and Vietnam. New Scientist

Vaccination by inhaling spray possible

"The spray needs two doses, spaced two weeks apart, compared to the injectable vaccine, which requires three doses over six months. Denise Nardelli-Haefliger at the University of Lausanne in Switzerland, who leads the team developing the vaccine, presented the results at the conference of the European Research Organization on Genital Infection and Neoplasia in Paris." New Scientist