Stories tagged medicine

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A bin of spares: for future-babies.
A bin of spares: for future-babies.
Courtesy Max Sparber
In many respects, the people of my country—we call it “Futureland” or “Futureworld,” depending on the state—are much like Lego men (minifigs). We have round, cheerful faces, chunky, clunky legs, and square, tapering shoulders. And the women… oh, the women of Futureland are the most beautiful in the world, with their round, cheerful faces, chunky, clunky legs, and square, tapering shoulders. Some might argue that they’re only distinguishable from us men by painted on lipstick and eyelashes… but I don’t see why that has to be a bad thing.

And, like Lego people, our arms are removable and replaceable. We can mix and match! Unfortunately, the process of arm removal is often extremely painful and bloody, and arm replacement involves extensive surgery, an anti-rejection drug regimen, and years of physical therapy. Still… replaceable arms! Yes, life in the future is fine indeed.

Oh? You don’t believe me? Well, put on your chronohats and futurnaut undies and join me up here for a moment, so that we might consider the case of one Karl Merk.

Karl was a German dairy farmer until six years ago, when he elected to have his arms removed. Although… Maybe “elected” isn’t totally accurate. Mr. Merk’s arms were detached just below the shoulders by a combine harvester, and he was screaming “Kill me, kill me!” when he was later discovered by a colleague. So it seems possible that the arm-removal could have been an accident.

Regardless, it wasn’t until just recently that a suitable set of new arms could be found to click back into Karl’s shoulders.

It took a team of 40 surgeons, specialists, and support staff 15 hours to reattach the arms of a donor who had died only hours earlier. The arms were filled with “a cooled preservation solution,” and then detached from the donor’s shoulders at the exact point Mr. Merk’s arms were severed. Merk’s arm stumps were then cut open to expose the bone, muscle, nerve tissue, and blood vessels.

The bones were joined first, followed quickly by arteries and veins, to ensure blood flow. Muscles and tendons were then attached, followed by the nerves, and then the skin was finally sewn together.

Click. Click.

I recommend checking out the video in the page linked to above (under “the case of one Karl Merk”). It has a video of Karl with his new arms. The arms are paler than the rest of Karl, and they look kind of muscley. They’re also kind of wet and shiny looking, which is gross. But they work, and over the next couple years Karl should be able to regain full use of the hands and everything. Because so much of his arms were cut off in the accident, there’s a greater risk that Karl’s body won’t accept the new limbs, but so far there doesn’t signs of rejection.

And that’s life in the future. Tons of painful surgery. And maybe some slightly disproportionally large arms.

Buzz has plenty on organ transplants and the like. Check in out here.

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The cure for what ails you: But only if you can get it in time.
The cure for what ails you: But only if you can get it in time.
Courtesy Destinys Agent

(With the Republican National Convention literally across the street, the Science Museum of Minnesota will be closed starting Friday, August 29. But Science Buzz marches on! To honor our convention guests, I’ll be posting entries focusing on issues where science and politics overlap. Hopefully this will spur some discussion. Or at least tick some people off. Previous entries here and here.)

Getting a new drug approved for use is a long and arduous process. As well it should be—we need to be sure not only that the drug works, but also that it doesn’t have any nasty, even fatal, side-effects.

Unfortunately, the process has gotten slower lately. The US Food and Drug Administration is approving only half as many drugs as it did a decade ago. Some observers believe the organization has grown gun-shy. After Vioxx and a few other high-profile drugs had to be pulled from the market over safety concerns, the agency has become a lot more cautious.

(The cynical among us might say the FDA is out to protect its own skin, regardless of how many lives are lost by withholding drug approvals. At the same time, one can argue that they agency has been forced into its current cautious approach by the media and Congress, who heap criticism and blame on the FDA for its few mistakes, but never offer any praise for its many successes.)

Another issue arises from the pre-approval trials. New drugs are tested on a small number of patients. Often there are more patients interested in taking part in the trial than there are slots available. This can be especially difficult for terminally ill patients who have exhausted all other treatment options – nothing has worked, and they are still dying. They would have nothing to lose, and potentially a lot to gain, from trying an experimental drug. The drug trial itself might benefit from having more subjects. It’s win-win.

But getting such patients added to trials has proven very difficult. In May, Sen. Sam Brownback (R., Kan.) and Rep. Diane Watson (D., Calif.) introduced a bill to open up access to trials for such patients. No action was taken before Congress recessed for the summer.

Researchers in London have found that oxytocin – a naturally-produced human hormone – can help combat shyness. They are also hoping to use it to address other conditions, including autism and depression.

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Broccoli: The Super Food
Broccoli: The Super Food
Courtesy FIR0002
New research coming out of Britain shows eating broccoli may reverse damage done by diabetes to heart and blood vessels. I’m always glad to hear anything new about the benefits of broccoli. Not that I have diabetes – I don’t. But broccoli is my favorite vegetable, and besides its potentially new vascular benefits, the leafy vegetable is high in fiber, full of vitamins C and K, and nutrients that have been found to reduce the risk of some cancers. A member of the cabbage family (Brassica), broccoli, along with other vegetables in the genus (including brussel sprouts, cauliflower, turnips, kohlrabi, and mustard seed) has been linked to the reduction of strokes and heart attacks.

Diabetes is a serious metabolic disorder resulting in abnormally high levels of blood sugar (hyperglycemia). The disease can affect nearly every part of the body, and left untreated can lead to blindness, kidney failure, nerve damage, and loss of limb. Diabetics have up to 5 times the risk of suffering from vascular diseases such as heart attacks, strokes because of damaged blood vessels.

The current research involves the anti-cancer compound sulforaphane, a product of another compound found in broccoli called glucoraphanin. Sulforaphane encourages production of enzymes that protect blood vessels, and reduce levels of cell-damaging molecules. When researchers at the University of Warwick tested the effects of sulforaphane on blood vessels damaged by hyperglycemia (high sugar levels), they noticed a nearly 75% reduction of Reactive Oxygen Species (ROS) molecules in the body. High levels of ROS -the result of increased blood sugar- can damage cells. The researchers noted sulforaphane also protected cells by triggering a protein that activated antioxidant enzymes.

“Our study suggests that compounds such as sulforaphane from broccoli may help counter processes linked to the development of vascular disease in diabetes,” said Professor Paul Thornalley of the University of Warwick. His team’s appears in the journal Diabetes. Thornalley added that he expects future tests of a brassica vegetable-rich diet could yield further health benefits for diabetic patients.

"It is encouraging to see that Professor Thornalley and his team have identified a potentially important substance that may protect and repair blood vessels from the damaging effects of diabetes,” said Dr Iain Frame, director of research at the charity Diabetes UK. "It also may help add some scientific weight to the argument that eating broccoli is good for you."

That brings to mind the time when the first president Bush said since he was president he didn’t have to eat broccoli anymore. (I think the quote was “Read my lips: no more broccoli”) Well, good for him. It just means more of the natural, leafy panacea for the rest of us.

SOURCE and LINKS
BBC website story
American Diabetes Association
More on broccoli

The HIV virus attacks white blood cells by latching onto a protein on their surface. People without that protein are immune from AIDS. Using that knowledge, scientists in Pennsylvania have figured out how to genetically manipulate mice so they, too, have the immunity.

The procedure has not yet been tested on humans. If it does work, it wouldn’t cure the disease, but it could let infected persons live healthier lives with the virus.

Cellphones and cancer

by Gene on Jun. 29th, 2008
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Do they or don’t they? For years, we’ve been hearing rumors that holding a cellphone right next you’re your brain wasn’t the wisest thing in the world, as some suspected it may cause cancer. And for years, we’ve been hearing experts, including the American Cancer Society, insist there was no firm evidence of a link. But now some surgeons are raising the question again.

A new study is underway in Britain to try and resolve the question.

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Herpes is on the rise in New York city – one in four adults carries the disease.

And HIV is on the rise across the United States – though experts say that is due to better, more accurate counting rather than to any real increase in the disease.

On the plus side of the ledger, the World Health Organization has recognized that AIDS is unlikely to become an epidemic among heterosexual (straight) populations in the West. Not that folks can all go about being careless, but it is far less common than many feared it would be. The disease is epidemic among all groups in sub-Saharan Africa.

And, just in time for the pool party season, comes news that you can't catch AIDS from swimming pool water, even if people have been engaging in natatorial naughtiness.

Researchers at the University of Missouri have found that dried tomato powder helps protect against prostate cancer. If this pans out and leads to a viable treatment, that will be good news – recently the Agency for Healthcare Research and Quality reviewed a variety of treatments, and found that none of them stood out as superior.

As the Mississippi flood waters recede, a new threat is rising. Public health officials in Iowa are warning people about the health risks associated with cleaning up their water-damaged homes, farms and buildings. Bacteria thrives in the water, and could lead to a number of diseases, and can contaminate well water. Water-logged buildings are a haven for mold, which can cause serious problems for allergy and asthma sufferers.

The recent death of TV newsman Tim Russert has blogger and journalist Marty Nemko thinking about men’s health issues – how they are addressed in research, and how they are portrayed in the media.